BBPUC 2024 – Cases
Below are links to the Virtual Pathology files for the 10 cases which will be discussed during the course.
Please review the cases which are hosted with our friends at Leeds Virtual Pathology, click on case image to open Virtual Pathology Page. You are then invited to use the Mentimeter link at bottom of page to submit the diagnoses. Full correct diagnoses and discussion will be given during the course by Dr Elena Provenzano, Dr Bruce Tanchel and Professor Abeer Shaaban.
BBPUC 2024 - Slide Case Answers
Click HERE to download Answers to the Slide Cases
Dr Elena Provenzano
Chief Pathologist
Cambridge University Hospitals NHS Foundation Trust
1
History:
33 year old female. Total duct excision for bloody nipple discharge
MCQ/Differential
1. Benign intraduct papilloma
2. Intraduct papilloma with DCIS
3. Encapsulated papillary carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
ER
Smooth Muscle Myosin
CK 5/6
2
History:
66 year old female. Excision B3 lesion.
MCQ/Differential
1. Papilloma with squamous metaplasia
2.Papilloma with low grade adenosquamous carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
p63
ER
CK14
Smooth Muscle Myosin
BBPUC 2024 - Slide Case Answers
Click HERE to download Answers to the Slide Cases
Dr Soha El Sheikh
Honorary Associate Professor
University College London
3
History:
48 yr old woman with a previous history of TNBC. Now swelling and oedema near WLE scar. Punch biopsy.
MCQ/Differential
1.Recurrent triple negative breast carcinoma
2. Angiosarcoma
3. melanoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
4
History:
89 yr old woman with a hypoechoic breast mass.
MCQ/Differential
1.invasive ductal NST
2.Solid papillary carcinoma with extensive invasion
3.neuroendocrine carcinoma
4. solid adenoid cystic carcinoma
5.Metastatic carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
BBPUC 2024 - Slide Case Answers
Click HERE to download Answers to the Slide Cases
Professor Cecily Quinn
Consultant Histopathologist
St. Vincent’s University Hospital (SVUH), Dublin, Ireland
5
History:
Female, 26 years
Right breast: c/o enlarging lump, 45mm on imaging with cystic spaces, R3
Slide from needle core biopsy.
MCQ/Differential
1. High-grade carcinoma
2. Angiosarcoma
3. Malignant phyllodes tumour
4. Sarcoma, not otherwise specified
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
6
History:
Female, 42 years
Right breast: 6 mm hypoechoic lesion on baseline mammogram, R3
Slide from resection specimen
MCQ/Differential
1. Adenomamyoepitheliosis
2. Intraduct papilloma
3. Ductal adenoma
4. Radial scar
5. Adenomyoepithelioma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
BBPUC 2024 - Slide Case Answers
Click HERE to download Answers to the Slide Cases
Dr Bruce Tanchel
Consultant Histopathologist
Heartlands Hospital, Birmingham
7
History:
Right breast core biopsy. Irregular mass seen with bruising. Recent trauma. Suspicious.
Previous histology: Prior left breast cancer.
MCQ/Differential
1. Primary Breast Sarcoma
2. Spindle Cell Carcinoma
3. Angiosarcoma
4. Adenomyoepithelioma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
BBPUC 2024 - Slide Case Answers
Click HERE to download Answers to the Slide Cases
Professor Abeer Shaaban
Consultant Pathologist
Queen Elizabeth Hospital Birmingham
8
History:
40 yr old, left breast mass ? fibroadenoma
MCQ/Differential
- Pleomorphic adenoma
- Matrix producing metaplastic carcinoma
- Metastatic carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
9
History:
History of WLE for breast cancer 3 years ago followed by radiotherapy. Mass in same breast
MCQ/Differential
1. Angiosarcoma
2. Radiation association sarcoma
3. Metaplastic carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
P63
10
History:
42 year old left breast lump, diagnostic excision
X2 H&E slides
MCQ/Differential
1. Mammary hamartoma
2. Benign phyllodes tumour
3. Borderline phyllodes tumour
4. Malignant phyllodes tumour
5. Periductal stromal tumour
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
H&E
BBPUC 2024 - Slide Case Answers
Click HERE to download Answers to the Slide Cases