BBPUC 2023 – Cases
Below are links to the Virtual Pathology files for the 9 cases which will be discussed during the course.
Please review the cases which are hosted with our friends at Leeds Virtual Pathology, click on case image to open Virtual Pathology Page. You are then invited to use the Mentimeter link at bottom of page to submit the diagnoses. Full correct diagnoses and discussion will be given during the course by Dr Elena Provenzano, Dr Bruce Tanchel and Professor Abeer Shaaban.
BBPUC 2023 – Slide Case Answers
Click HERE to download Answers to the Slide Cases
Dr Elena Provenzano
Chief Pathologist
Cambridge University Hospitals NHS Foundation Trust
1
History:
60 year old female presenting with lump left axillary tail (grew up in Africa)
MCQ/Differential
1. Metaplastic squamous cell carcinoma breast
2. Metastatic squamous cell carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
2
History:
76 year old female presenting with central left breast mass and associated axillary lymphadenopathy. Past history of Myeloma.
MCQ/Differential
1. Grade 3 invasive carcinoma NST with LN metastasis
2. Grade 3 invasive carcinoma NST with myeloma in node
3. Myeloma involving breast and LN
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
Breast Core Biopsy
Axillary Node Biopsy
BBPUC 2023 – Slide Case Answers
Click HERE to download Answers to the Slide Cases
Dr Bruce Tanchel
Consultant Histopathologist
Heartlands Hospital, Birmingham
3
History:
72 year old female. Multifocal/centric R4/R5 tumours in the left breast. Normal nodes.
MCQ/Differential
1. Ductal NST carcinoma with nodal metastasis
2. Solid basaloid adenoid cystic carcinoma with nodal metastasis
3. Cylindroma in breast and lymph node
4. Neuroendocrine breast carcinoma with nodal metastasis
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E Breast
CKIT
Axillary LN
4
History:
91 year old female. P4/5 right axilla, core biopsy taken. No visible lesion in the breast.
MCQ/Differential
1. Metastatic lobular carcinoma
2. Metastatic non mammary carcinoma
3. Lymphoma
4. Melanoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
BBPUC 2023 – Slide Case Answers
Click HERE to download Answers to the Slide Cases
Professor Abeer Shaaban
Consultant Pathologist
Queen Elizabeth Hospital Birmingham
5
History:
45 year-old female. Section from mastectomy specimen
MCQ/Differential
1. DCIS
2. DCIS and invasive ductal carcinoma
3. P LCIS and invasive lobular carcinoma
4. DCIS, PLCIS, invasive lobular carcinoma
5. DCIS and invasive histiocytic carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
6
History:
70 year old female, diagnostic excision
MCQ/Differential
1. LCIS
2. DCIS
3. Hamartoma with DCIS
4. Fibroadenoma with DCIS and LCIS
5. Fibroadenomas with ADH
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
7
History:
Second opinion, 87 year old female, core biopsy, U4
MCQ/Differential
1. Complex sclerosing lesion
2. Adeno squamous carcinoma
3. Salivary-like carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
8
History:
73 year old female, core biopsy from a suspicious solid and cystic lesion
MCQ/Differential
1. Complex sclerosing lesion with PASH
2. Chronic inflammation with reactive stroma
3. Invasive carcinoma
4. Fibroepithelial lesion with chronic inflammation
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
9
History:
Second opinion, 65-year-old female, section from symptomatic breast lump
MCQ/Differential
1. Intraduct papilloma with epithelial hyperplasia
2. Encapsulated papillary carcinoma
3. Tall Cell Carcinoma with Reversed Polarity
4. Solid papillary carcinoma
Virtual Pathology Links
Please click on the image to have slide open up in the Leeds Virtual Pathology viewer
H&E
BBPUC 2023 – Slide Case Answers
Click HERE to download Answers to the Slide Cases